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FINANCE | Investment Firms & Funds
perceptivelife.com

Investments

281

Portfolio Exits

122

Funds

12

Partners & Customers

2

About Perceptive Advisors

Perceptive Advisors is a privately owned hedge fund sponsor that invests in biotechnology and life sciences sectors in public equity markets across the globe. It employs a long/short equity strategy as a hedging technique while making its investments. The company was founded in 1999 and is based in New York, New York.

Headquarters Location

51 Astor Place 10th Floor

New York, New York, 10003,

United States

646-205-5340

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Latest Perceptive Advisors News

Trinity Biotech Welcomes Perceptive Advisor’s Indication of Potential Debt-to-Equity Conversion - Strengthening Balance Sheet and Supporting Growth

Oct 27, 2025

Trinity Biotech plc DUBLIN, Oct. 27, 2025 (GLOBE NEWSWIRE) -- Trinity Biotech plc (Nasdaq: TRIB), a commercial-stage biotechnology company focused on human diagnostics and diabetes management solutions, including wearable biosensors, today announced that the Company welcomes the indicated intention of its largest investor and primary lender, Perceptive Advisors, to submit a proposal that, if implemented, would facilitate the conversion of a portion of the Company’s outstanding debt and other obligations into equity. The Company believes this strategic initiative represents a constructive step toward strengthening its balance sheet and that an equitization program, if successfully executed, could enhance the Company’s financial flexibility and support its ambitious growth objectives. Perceptive Advisors is a leading life sciences investment firm that has continued to be a supportive and constructive investment partner to the Company through its recent transformation journey. The Company looks forward to engaging in discussions that are mutually beneficial and aligned with the interests of all of its stakeholders, including shareholders. Forward-Looking Statements This release includes statements that constitute “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 (the “Reform Act”), including but not limited to statements related to Trinity Biotech’s cash position, financial resources and potential for future growth, market acceptance and penetration of new or planned product offerings, and future recurring revenues and results of operations. Trinity Biotech claims the protection of the safe harbor for forward-looking statements contained in the Reform Act. These forward-looking statements are often characterized by the terms “may,” “believes,” “projects,” “expects,” “anticipates,” or words of similar import, and do not reflect historical facts. Specific forward-looking statements contained in this release may be affected by risks and uncertainties, including, but not limited to, our ability to capitalize on the Waveform transaction and of our recent acquisitions, our continued listing on the Nasdaq Stock Market, the impact of the U.S. government shut-down, our ability to achieve profitable operations in the future, the impact of the spread of COVID-19 and its variants, the possible pause and/or disruption in U.S. Government funding for HIV tests produced by Trinity Biotech, potential excess inventory levels and inventory imbalances at the company’s distributors, losses or system failures with respect to Trinity Biotech’s facilities or manufacturing operations, the effect of exchange rate fluctuations on international operations, fluctuations in quarterly operating results, dependence on suppliers, the market acceptance of Trinity Biotech’s products and services, the continuing development of its products, required government approvals, risks associated with manufacturing and distributing its products on a commercial scale free of defects, risks related to the introduction of new instruments manufactured by third parties, risks associated with competing in the human diagnostic market, risks related to the protection of Trinity Biotech’s intellectual property or claims of infringement of intellectual property asserted by third parties and risks related to condition of the United States economy and other risks detailed under “Risk Factors” in Trinity Biotech’s annual report on Form 20-F for the fiscal year ended December 31, 2024 and Trinity Biotech’s other periodic reports filed from time to time with the United States Securities and Exchange Commission. Forward-looking statements speak only as of the date the statements were made. Trinity Biotech does not undertake and specifically disclaims any obligation to update any forward-looking statements. About Trinity Biotech Trinity Biotech is a commercial stage biotechnology company focused on diabetes management solutions and human diagnostics, including wearable biosensors. The Company develops, acquires, manufactures and markets diagnostic systems, including both reagents and instrumentation, for the point-of-care and clinical laboratory segments of the diagnostic market and has recently entered the wearable biosensor industry, with the acquisition of the biosensor assets of Waveform Technologies Inc. and intends to develop a range of biosensor devices and related services, starting with a continuous glucose monitoring product. Our products are used to detect infectious diseases and to quantify the level of Haemoglobin A1c and other chemistry parameters in serum, plasma and whole blood. Trinity Biotech sells direct in the United States and through a network of international distributors and strategic partners in over 75 countries worldwide. For further information, please see the Company’s website:  www.trinitybiotech.com . About Perceptive Advisors Founded in 1999 and based in New York, NY, Perceptive Advisors is an investment management firm with approximately $8 billion in assets. Perceptive Advisors is focused on supporting the progress of the life sciences industry by identifying opportunities and directing financial resources to the most promising technologies in healthcare. For more information visit  www.perceptivelife.com . Contact:

Perceptive Advisors Investments

281 Investments

Perceptive Advisors has made 281 investments. Their latest investment was in Alto Neuroscience as part of their PIPE on October 20, 2025.

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Perceptive Advisors Investments Activity

investments chart

Date

Round

Company

Amount

New?

Co-Investors

Sources

10/20/2025

PIPE

Alto Neuroscience

$50M

Yes

4

10/7/2025

Series C

Affinia Therapeutics

$40M

No

7

9/17/2025

PIPE - III

Oruka Therapeutics

$180M

No

3

9/3/2025

Series B

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$XXM

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10

9/3/2025

Series C

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$XXM

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10

Date

10/20/2025

10/7/2025

9/17/2025

9/3/2025

9/3/2025

Round

PIPE

Series C

PIPE - III

Series B

Series C

Company

Alto Neuroscience

Affinia Therapeutics

Oruka Therapeutics

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Amount

$50M

$40M

$180M

$XXM

$XXM

New?

Yes

No

No

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Co-Investors

Sources

4

7

3

10

10

Perceptive Advisors Portfolio Exits

122 Portfolio Exits

Perceptive Advisors has 122 portfolio exits. Their latest portfolio exit was Astria Therapeutics on October 14, 2025.

Date

Exit

Companies

Valuation
Valuations are submitted by companies, mined from state filings or news, provided by VentureSource, or based on a comparables valuation model.

Acquirer

Sources

10/14/2025

Acq - Pending

$XXM

4

10/7/2025

Acq - P2P

$XXM

12

8/14/2025

Reverse Merger

$XXM

5

7/8/2025

Acq - Pending

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$XXM

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10

6/30/2025

Acquired

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$XXM

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10

Date

10/14/2025

10/7/2025

8/14/2025

7/8/2025

6/30/2025

Exit

Acq - Pending

Acq - P2P

Reverse Merger

Acq - Pending

Acquired

Companies

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Valuation

$XXM

$XXM

$XXM

$XXM

$XXM

Acquirer

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Sources

4

12

5

10

10

Perceptive Advisors Acquisitions

2 Acquisitions

Perceptive Advisors acquired 2 companies. Their latest acquisition was Synthego on June 26, 2025.

Date

Investment Stage

Companies

Valuation
Valuations are submitted by companies, mined from state filings or news, provided by VentureSource, or based on a comparables valuation model.

Total Funding

Note

Sources

6/26/2025

Debt

$XXM

$472.25M

Asset Sale

2

9/20/2024

Series D

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$XXM

$XXM

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10

Date

6/26/2025

9/20/2024

Investment Stage

Debt

Series D

Companies

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Valuation

$XXM

$XXM

Total Funding

$472.25M

$XXM

Note

Asset Sale

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Sources

2

10

Perceptive Advisors Fund History

12 Fund Histories

Perceptive Advisors has 12 funds, including Perceptive Xontogeny Venture Fund II.

Closing Date

Fund

Fund Type

Status

Amount

Sources

5/12/2021

Perceptive Xontogeny Venture Fund II

$515M

1

11/16/2020

Perceptive Credit Opportunities Fund III

$1,100M

5

9/1/2020

Perceptive Credit Opportunities Offshore Fund III

$297.9M

2

9/1/2020

Perceptive Credit Opportunities III SLP

$XXM

10

12/10/2019

Perceptive Xontogeny Venture Fund

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$XXM

10

Closing Date

5/12/2021

11/16/2020

9/1/2020

9/1/2020

12/10/2019

Fund

Perceptive Xontogeny Venture Fund II

Perceptive Credit Opportunities Fund III

Perceptive Credit Opportunities Offshore Fund III

Perceptive Credit Opportunities III SLP

Perceptive Xontogeny Venture Fund

Fund Type

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Status

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Amount

$515M

$1,100M

$297.9M

$XXM

$XXM

Sources

1

5

2

10

10

Perceptive Advisors Partners & Customers

2 Partners and customers

Perceptive Advisors has 2 strategic partners and customers. Perceptive Advisors recently partnered with Cooley on June 6, 2024.

Date

Type

Business Partner

Country

News Snippet

Sources

6/17/2024

Vendor

United States

1

8/11/2020

Partner

China

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10

Date

6/17/2024

8/11/2020

Type

Vendor

Partner

Business Partner

Country

United States

China

News Snippet

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Sources

1

10

Perceptive Advisors Team

12 Team Members

Perceptive Advisors has 12 team members, including current Founder, Chief Executive Officer, Joseph Edelman.

Name

Work History

Title

Status

Joseph Edelman

Aries Capital Partners, and Prudential

Founder, Chief Executive Officer

Current

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Name

Joseph Edelman

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Work History

Aries Capital Partners, and Prudential

Title

Founder, Chief Executive Officer

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Status

Current

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